MRD Strategic Steering Working Group
Angela Silvestro
Director, Companion Diagnostics
GSK
Co-Chairs
Jim Godsey, PhD
Scientific Co-Chair
BLOODPAC
Current Projects
The MRD Strategic Steering WG is working on defining the next MRD projects:
Demonstrate MRD Clinical Utility: Launch a new WG to focus on demonstrating the clinical utility of MRD testing, complementing ongoing efforts on MRD clinical validation approaches.
Support guideline integration: Develop recommendations and guidance to accelerate inclusion of solid tumor MRD intended uses in the NCCN Guidelines.
Pursue Early Endpoint designation: Create a dedicated WG to advance MRD testing toward Early Endpoint status in adjuvant therapy trials, strengthening the link between MRD results and long-term patient outcomes.
Support the new DLBCL working group efforts in developing frameworks and standards for MRD clinical implementation.
Participating Organizations
Adela, Biofidelity, Bristol Myers Squibb, Exact Sciences, Freenome, Friends of Cancer Research, GSK, Guardant Health, Johnson & Johnson, Merck, Natera, NeoGenomics, PreAnalytiX, Roche
Meetings
This working group meets on zoom every other Tuesday from 4:00 - 5:00 PM EST.
Special workshops and sessions:
June 25, 2025: In-person workshop in Boston

