MRD Strategic Steering Working Group

Angela Silvestro

Director, Companion Diagnostics

GSK

Co-Chairs

Jim Godsey, PhD

Scientific Co-Chair

BLOODPAC

Current Projects

The MRD Strategic Steering WG is working on defining the next MRD projects:

  • Demonstrate MRD Clinical Utility: Launch a new WG to focus on demonstrating the clinical utility of MRD testing, complementing ongoing efforts on MRD clinical validation approaches.

  • Support guideline integration: Develop recommendations and guidance to accelerate inclusion of solid tumor MRD intended uses in the NCCN Guidelines.

  • Pursue Early Endpoint designation: Create a dedicated WG to advance MRD testing toward Early Endpoint status in adjuvant therapy trials, strengthening the link between MRD results and long-term patient outcomes.

  • Support the new DLBCL working group efforts in developing frameworks and standards for MRD clinical implementation.

Participating Organizations

Adela, Biofidelity, Bristol Myers Squibb, Exact Sciences, Freenome, Friends of Cancer Research, GSK, Guardant Health, Johnson & Johnson, Merck, Natera, NeoGenomics, PreAnalytiX, Roche

Past Deliverables

Meetings

This working group meets on zoom every other Tuesday from 4:00 - 5:00 PM EST.

Special workshops and sessions:

June 25, 2025: In-person workshop in Boston